In Oracle VirtualBox, it is possible to add one or more DVD or CD-ROM drives to a virtual machine. Drives can be connected to a physical DVD or CD-ROM drives or ISO images.
Here is how it can be done:
Select the virtual machine from the Oracle VM VirtualBox Manager and click Settings:
Click Storage>Add CD/DVD Device:
Select whether you want to connect the drive to a physical drive or an ISO image file:
Press OK to save the changes.